151657

• Gene Symbol: Shc1
• Gene Name: src homology 2 domain-containing transforming protein C1
• Gene Aliases: Shc, ShcA, p66, p66shc
• Chromosome Location: Chr.3: 89418481 - 89430029 on Build GRCm38
• UniGene ID: Mm.86595
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Shc1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113331.2	NP_001106802.1	2	770
	NM_011368.5	NP_035498.2	3	372
GenBank mRNA	AK036980.1	-	1	2338
	AK049357.1	-	3	345
	AK155158.1	-	2	765
	AK203451.1	-	2	193
	AK211173.1	-	2	190
	BC036172.1	-	3	323	4988907
	BY341731.1	-	2	205
	U15784.1	-	3	262

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053517, NM_001164060, D83015, BC088298.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
signal transduction
epidermal growth factor receptor signaling pathway
heart development
aging
insulin receptor signaling pathway
single organismal cell-cell adhesion
actin cytoskeleton organization
neuron differentiation
neuron projection development
actin cytoskeleton reorganization
intracellular signal transduction
regulation of growth
regulation of cell proliferation
positive regulation of DNA replication
positive regulation of vasoconstriction
positive regulation of smooth muscle cell proliferation

Function(s)

phosphotyrosine binding
epidermal growth factor receptor binding
insulin receptor binding
insulin-like growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
protein kinase binding
receptor tyrosine kinase binding
protein complex binding
ephrin receptor binding
phosphoprotein binding
protein phosphatase 2A binding