151955

Gene Symbol:

Pnp2 Pnp

Gene Name:

purine-nucleoside phosphorylase 2

purine-nucleoside phosphorylase

Gene Aliases:

-

AL024301, AU015798, Np, Np-1, Np-2, Pnp1

Chromosome Location:

Chr.14: 50956141 - 50964749 on Build GRCm38

Chromosome Location:

Chr.14: 50944303 - 50953412 on Build GRCm38

UniGene ID:

Mm.482171

Mm.17932

Species:

Mouse

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Pnp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001123371.2	NP_001116843.1	6	744
GenBank mRNA	AK008143.1	-	6	748

Gene Symbol: Pnp
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013632.4	NP_038660.1	6	947
GenBank mRNA	AK049817.1	-	6	726
	AK153451.1	-	6	949
	BC003788.1	-	6	719	3600212
	BC052679.1	-	6	698	30062908
	CT010254.1	-	5	667
	CT010316.1	-	5	667
	L11290.1	-	6	688
	L11291.1	-	6	688
	M84563.1	-		745
	U35374.1	-	5	667
	X56548.1	-	6	744

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_006251857, FQ225955, FQ228749, FQ209687, FQ219529, and others.

Panther Classification:

Molecular Function -

kinase, nucleotide kinase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

biological_process
purine-containing compound salvage
positive regulation of T cell mediated cytotoxicity
nucleobase-containing compound metabolic process
inosine catabolic process
deoxyinosine catabolic process
deoxyguanosine catabolic process
GTP biosynthetic process
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
nucleoside metabolic process
response to gamma radiation
urate biosynthetic process
positive regulation of T cell proliferation
purine nucleoside metabolic process
positive regulation of B cell differentiation
positive regulation of DNA repair
dGTP metabolic process
guanosine catabolic process
positive regulation of alpha-beta T cell differentiation
negative regulation of T cell apoptotic process

Function(s)

nucleoside binding
purine nucleobase binding
purine-nucleoside phosphorylase activity
drug binding
phosphate ion binding
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring pentosyl groups