151960

• Gene Symbol: Pou5f1
• Gene Name: POU domain, class 5, transcription factor 1
• Gene Aliases: NF-A3, Oct-3, Oct-3/4, Oct-4, Oct3, Oct3/4, Oct4, Otf-3, Otf-4, Otf3, Otf3-rs7, Otf3g, Otf4
• Chromosome Location: Chr.17: 35506032 - 35510777 on Build GRCm38
• UniGene ID: Mm.17031
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pou5f1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001252452.1	NP_001239381.1	4, 5	506
	NM_013633.3	NP_038661.2	4, 5	868
GenBank mRNA	AB221654.1	-	4, 5	800
	AK145321.1	-	4, 5	839
	BC068268.1	-	4, 5	844	30019896
	HM346526.1	-	2, 3	120
	M34381.1	-	4, 5	849
	X52437.1	-	4, 5	747

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
mesodermal cell fate commitment
endodermal cell fate commitment
ectodermal cell fate commitment
endodermal cell fate specification
trophectodermal cell differentiation
blastocyst growth
BMP signaling pathway involved in heart induction
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
response to organic substance
regulation of gene expression
stem cell population maintenance
germ-line stem cell population maintenance
response to retinoic acid
somatic stem cell population maintenance
positive regulation of catenin import into nucleus
mRNA transcription from RNA polymerase II promoter
cell fate commitment
negative regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of calcium ion-dependent exocytosis
stem cell differentiation
positive regulation of protein kinase B signaling
negative regulation of protein kinase B signaling
positive regulation of SMAD protein import into nucleus
cell fate commitment involved in formation of primary germ layer
cardiac cell fate determination
negative regulation of gene silencing by miRNA
regulation of heart induction by regulation of canonical Wnt signaling pathway
regulation of methylation-dependent chromatin silencing

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
transcription factor binding
chromatin DNA binding
ubiquitin protein ligase binding
miRNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
protein heterodimerization activity
POU domain binding
HMG box domain binding