152804

• Gene Symbol: Picalm
• Gene Name: phosphatidylinositol binding clathrin assembly protein
• Gene Aliases: CALM, CLTH, PAP180, fit-1, fit1, mKIAA4114
• Chromosome Location: Chr.7: 90130220 - 90209447 on Build GRCm38
• UniGene ID: Mm.235175
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Picalm
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001252520.1	NP_001239449.1	8	1133
	NM_001252521.1	NP_001239450.1	8	1133
	NM_001252522.1	NP_001239451.1	8	1133
	NM_001252523.1	NP_001239452.1	8	1133
	NM_001252524.1	NP_001239453.1	8	1133
	NM_146194.4	NP_666306.2	8	1133
GenBank mRNA	AK085472.2	-	5	367
	AK144960.1	-	8	872
	AK162360.1	-	8	826
	AK165066.1	-	3	244
	AK170373.1	-	8	1153
	AK220291.1	-	8	849
	AY206701.1	-	8	817
	BC011470.1	-	8	843	2651109
	BC021491.1	-	8	1082	5345558
	BC023843.1	-	8	881	5346041
	BC025566.1	-	8	1156	5322606
	BC027116.1	-	5	444
	BC057683.1	-	8	1084	3671962

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053554, XM_006229676, XM_006229674, XM_006229681, XM_006229679, and others.

Panther Classification:

Molecular Function -

vesicle coat protein

Gene Ontology Categories:

Process(es)

endocytosis
receptor-mediated endocytosis
multicellular organism development
axonogenesis
cell proliferation
negative regulation of gene expression
synaptic vesicle maturation
vesicle-mediated transport
endosomal transport
hemopoiesis
regulation of endocytosis
receptor internalization
regulation of protein localization
cargo loading into vesicle
positive regulation of transcription, DNA-templated
negative regulation of receptor-mediated endocytosis
clathrin coat assembly
dendrite morphogenesis
regulation of protein transport
iron ion homeostasis
clathrin-mediated endocytosis
iron ion import into cell
positive regulation of neuron death
positive regulation of beta-amyloid formation
regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Function(s)

phospholipid binding
1-phosphatidylinositol binding
SH3 domain binding
clathrin binding
clathrin heavy chain binding
clathrin adaptor activity
identical protein binding