1531

• Gene Symbol: CDKN1A
• Gene Name: cyclin dependent kinase inhibitor 1A
• Gene Aliases: CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1
• Chromosome Location: Chr.6: 36676460 - 36687339 on Build GRCh38
• UniGene ID: Hs.370771
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDKN1A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000389.4	NP_000380.1	3	1022
	NM_001220777.1	NP_001207706.1	3	967
	NM_001220778.1	NP_001207707.1	3	1132
	NM_001291549.1	NP_001278478.1	4	1174
	NM_078467.2	NP_510867.1	4	969
GenBank mRNA	AB209881.1	-	3	979
	AK298901.1	-	3	1030
	AK309512.1	-	4	868
	BC000275.1	-	3	962	3355833
	BC000312.2	-	3	1116	2821049
	BC001935.1	-	3	977	2823668
	BC013967.2	-	3	980	2822909
	L25610.1	-	3	975
	L26165.1	-	3	975
	U03106.1	-	3	972
	U09579.1	-	3	991

More Information

Panther Classification:

Molecular Function -

protein-binding activity modulator, kinase inhibitor, kinase modulator

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle arrest
Ras protein signal transduction
negative regulation of cell proliferation
response to toxic substance
response to X-ray
response to organonitrogen compound
negative regulation of gene expression
negative regulation of cell growth
positive regulation of B cell proliferation
organ regeneration
cellular response to extracellular stimulus
regulation of protein import into nucleus, translocation
cellular response to amino acid starvation
cellular response to heat
negative regulation of phosphorylation
response to drug
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
positive regulation of programmed cell death
negative regulation of cyclin-dependent protein serine/threonine kinase activity
response to arsenic-containing substance
positive regulation of fibroblast proliferation
protein stabilization
response to corticosterone
response to hyperoxia
intestinal epithelial cell maturation
cellular response to ionizing radiation
cellular response to UV-B
mitotic cell cycle arrest
cellular senescence
replicative senescence
stress-induced premature senescence
intrinsic apoptotic signaling pathway
positive regulation of cyclin-dependent protein kinase activity
negative regulation of G1/S transition of mitotic cell cycle
regulation of DNA biosynthetic process
positive regulation of reactive oxygen species metabolic process

Function(s)

cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
cyclin-dependent protein kinase activating kinase activity
cyclin binding
ubiquitin protein ligase binding
protein complex binding
metal ion binding