154621

• Gene Symbol: Dlc1
• Gene Name: deleted in liver cancer 1
• Gene Aliases: A730069N07Rik, Arhgap7, HP, STARD12, dlc-1
• Chromosome Location: Chr.8: 36567739 - 36953165 on Build GRCm38
• UniGene ID: Mm.125155
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dlc1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001194940.2	NP_001181869.1	2	1256
GenBank mRNA	AK043205.1	-	2	1238
	AK045326.1	-	2	1251
	AK053142.1	-	2	1171
	HM008381.1	-	1	809

More Information

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, GTPase-activating protein

Gene Ontology Categories:

Process(es)

neural tube closure
heart morphogenesis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cytoskeleton organization
signal transduction
activation of phospholipase C activity
negative regulation of cell proliferation
regulation of cell shape
hindbrain morphogenesis
actin cytoskeleton organization
negative regulation of cell migration
forebrain development
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
negative regulation of Rho protein signal transduction
positive regulation of protein dephosphorylation
positive regulation of GTPase activity
focal adhesion assembly
negative regulation of stress fiber assembly
negative regulation of focal adhesion assembly
positive regulation of execution phase of apoptosis

Function(s)

GTPase activator activity
lipid binding
vinculin binding
SH2 domain binding
phospholipase binding