15506

• Gene Symbol: MECP2
• Gene Name: methyl-CpG binding protein 2
• Gene Aliases: AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
• Chromosome Location: Chr.X: 154021800 - 154097731 on Build GRCh38
• UniGene ID: Hs.200716
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MECP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001110792.1	NP_001104262.1	2	288
	NM_001316337.1	NP_001303266.1	4	580
	NM_004992.3	NP_004983.1	3	412
	XM_005274682.4	XP_005274739.1	4	486
	XM_006724819.3	XP_006724882.1	2	272
	XM_011531166.2	XP_011529468.1	2	299
	XM_017029533.1	XP_016885022.1	6	912
GenBank mRNA	AF158180.1	-	3	353
	AJ132917.1	-	2	261
	AK289444.1	-	3	387
	AY541280.1	-	2	229
	BC011612.1	-	2	270	3956518
	BI767019.1	-	4	511
	BX538060.1	-	2	278
	DQ656049.2	-	2	317
	DQ656051.2	-	3	465
	GQ203293.1	-	3	412
	GQ203294.1	-	3	412
	GQ203295.1	-	3	412
	GQ896382.1	-	3	412
	GU479943.1	-	3	412
	GU812285.1	-	2	186
	GU812286.1	-	2	186
	HM020402.1	-	3	412
	HM156732.1	-	3	412
	HM156733.1	-	3	412
	HQ127345.1	-	2	186
	HQ141377.1	-	2	186
	HQ141378.1	-	3	412
	HQ154629.1	-	3	412
	KU178174.1	-	2	186
	KU178175.1	-	2	186
	KU178176.1	-	2	186
	L37298.1	-	2	267
	X89430.1	-	1	160
	X99686.1	-	2	260
	Y12643.1	-	2	250

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022673, XM_006229566, XM_006229567, M94064, DQ897369, and others.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
behavioral fear response
response to hypoxia
startle response
neurological system process involved in regulation of systemic arterial blood pressure
regulation of respiratory gaseous exchange by neurological system process
inositol metabolic process
mitochondrial electron transport, ubiquinol to cytochrome c
chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
glutamine metabolic process
cellular biogenic amine metabolic process
synapse assembly
heart development
respiratory gaseous exchange
long-term memory
locomotory behavior
protein localization
glucocorticoid metabolic process
positive regulation of cell proliferation
adult locomotory behavior
visual learning
response to radiation
pathogenesis
post-embryonic development
response to ionizing radiation
response to lead ion
dendrite development
histone methylation
histone acetylation
proprioception
sensory perception of pain
cerebellum development
ventricular system development
negative regulation of histone methylation
cardiolipin metabolic process
response to estradiol
negative regulation of histone acetylation
social behavior
neuron maturation
negative regulation of neuron apoptotic process
regulation of DNA methylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
phosphatidylcholine metabolic process
negative regulation of astrocyte differentiation
catecholamine secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
long-term synaptic potentiation

Function(s)

four-way junction DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
mRNA binding
protein binding
transcription factor binding
methyl-CpG binding
double-stranded methylated DNA binding
protein domain specific binding
chromatin DNA binding
siRNA binding
histone deacetylase binding
poly(A) RNA binding
unmethylated CpG binding
protein N-terminus binding