155231

• Gene Symbol: Smad1
• Gene Name: SMAD family member 1
• Gene Aliases: AI528653, Madh1, Madr1, Mlp1, MusMLP
• Chromosome Location: Chr.8: 79338395 - 79399468 on Build GRCm38
• UniGene ID: Mm.223717
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Smad1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008539.3	NP_032565.2	6	1532
GenBank mRNA	AK017583.1	-	6	1493
	AK054104.1	-	6	1493
	AK084505.1	-	6	1600
	AK158509.1	-	6	1548
	BC058693.1	-	6	1532	6811514
	U58992.1	-	5	1205
	U74359.1	-	6	1398

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013130, XM_006255397, XM_006255395, XM_006255394, XM_006255396, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

MAPK cascade
mesodermal cell fate commitment
osteoblast fate commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
protein phosphorylation
transforming growth factor beta receptor signaling pathway
SMAD protein complex assembly
gamete generation
negative regulation of cell proliferation
positive regulation of gene expression
BMP signaling pathway
midbrain development
hindbrain development
response to drug
homeostatic process
positive regulation of cell differentiation
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
cartilage development
cardiac muscle cell proliferation
bone development
positive regulation of cartilage development
cellular response to organic cyclic compound
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
identical protein binding
protein homodimerization activity
metal ion binding
protein heterodimerization activity
co-SMAD binding
I-SMAD binding