155679

• Gene Symbol: Nrp1
• Gene Name: neuropilin 1
• Gene Aliases: C530029I03, NP-1, NPN-1, Npn1, Nrp
• Chromosome Location: Chr.8: 128358285 - 128505476 on Build GRCm38
• UniGene ID: Mm.271745
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nrp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008737.2	NP_032763.2	8	1687
GenBank mRNA	AK082992.1	-	8	1740
	AK135428.1	-	8	1364
	AK141964.1	-	8	1479
	AK148372.1	-	8	1663
	AK149752.1	-	3	268
	AK159219.1	-	8	1478
	BC060129.1	-	8	1467	6409596
	D50086.1	-	8	1547

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001244972, NM_001244973, NM_001024629, NM_003873, NM_001024628, and others.
This siRNA also targets the following transcripts in Rat: NM_145098, XM_006255827, XM_008772598, XM_006255826, XM_006255825, and others.

Gene Ontology Categories:

Process(es)

angiogenesis
patterning of blood vessels
neuron migration
sprouting angiogenesis
cell migration involved in sprouting angiogenesis
multicellular organism development
nervous system development
axon guidance
axonal fasciculation
heart development
motor neuron axon guidance
organ morphogenesis
dendrite development
cell migration
peptidyl-tyrosine phosphorylation
facial nerve structural organization
trigeminal nerve morphogenesis
trigeminal nerve structural organization
vestibulocochlear nerve structural organization
nerve development
branchiomotor neuron axon guidance
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
cell differentiation
negative regulation of axon extension
retinal ganglion cell axon guidance
cellular response to hepatocyte growth factor stimulus
endothelial cell chemotaxis
cellular response to vascular endothelial growth factor stimulus
ventral trunk neural crest cell migration
vascular endothelial growth factor signaling pathway
VEGF-activated neuropilin signaling pathway
otic placode formation
negative regulation of neuron apoptotic process
platelet-derived growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway
hepatocyte growth factor receptor signaling pathway
sympathetic nervous system development
neuron development
regulation of axon extension involved in axon guidance
positive regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance
artery morphogenesis
axon extension involved in axon guidance
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
axonogenesis involved in innervation
dichotomous subdivision of terminal units involved in salivary gland branching
angiogenesis involved in coronary vascular morphogenesis
cell migration involved in coronary vasculogenesis
coronary artery morphogenesis
retina vasculature morphogenesis in camera-type eye
renal artery morphogenesis
sympathetic ganglion development
trigeminal ganglion development
ganglion morphogenesis
positive regulation of ERK1 and ERK2 cascade
semaphorin-plexin signaling pathway
commissural neuron axon guidance
regulation of retinal ganglion cell axon guidance
sensory neuron axon guidance
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
toxin transport
semaphorin-plexin signaling pathway involved in neuron projection guidance
semaphorin-plexin signaling pathway involved in axon guidance
positive regulation of retinal ganglion cell axon guidance
VEGF-activated neuropilin signaling pathway involved in axon guidance
protein localization to early endosome
facioacoustic ganglion development
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

vascular endothelial growth factor-activated receptor activity
protein binding
heparin binding
semaphorin receptor activity
growth factor binding
vascular endothelial growth factor binding
metal ion binding