15591

• Gene Symbol: IDE
• Gene Name: insulin degrading enzyme
• Gene Aliases: INSULYSIN
• Chromosome Location: Chr.10: 92451684 - 92574484 on Build GRCh38
• UniGene ID: Hs.500546
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IDE
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001322793.1	NP_001309722.1	3, 4	562
	NM_001322794.1	NP_001309723.1	3, 4	562
	NM_001322795.1	NP_001309724.1	4, 5	744
	NM_001322796.1	NP_001309725.1	3, 4	726
	NM_004969.3	NP_004960.2	3, 4	562
	NR_136399.1		3, 4	562
	XM_017016187.1	XP_016871676.1	3, 4	485
	XM_017016188.1	XP_016871677.1	3, 4	1079
	XM_017016189.1	XP_016871678.1	4, 5	478
	XM_017016190.1	XP_016871679.1	3, 4	605
GenBank mRNA	AK312810.1	-	3, 4	487
	BC096336.1	-	3, 4	526	40008464
	BC096337.1	-	3, 4	526	40008465
	BC096339.3	-	3, 4	526	40008468
	BX648462.1	-	3, 4	727
	M21188.1	-	3, 4	543

More Information

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
insulin receptor signaling pathway
determination of adult lifespan
bradykinin catabolic process
ubiquitin homeostasis
protein processing
positive regulation of protein oligomerization
hormone catabolic process
negative regulation of proteolysis
viral entry into host cell
beta-amyloid metabolic process
protein homooligomerization
protein homotetramerization
protein heterooligomerization
proteolysis involved in cellular protein catabolic process
insulin metabolic process
insulin catabolic process

Function(s)

beta-amyloid binding
virus receptor activity
glycoprotein binding
metalloendopeptidase activity
receptor binding
protein binding
ATP binding
zinc ion binding
ATPase activity
beta-endorphin binding
peptide binding
protein homodimerization activity
ubiquitin binding
insulin binding