156280

• Gene Symbol: Mdm2
• Gene Name: transformed mouse 3T3 cell double minute 2
• Gene Aliases: 1700007J15Rik, AA415488, Mdm-2
• Chromosome Location: Chr.10: 117688875 - 117710770 on Build GRCm38
• UniGene ID: Mm.22670
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mdm2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001288586.1	NP_001275515.1	11	1599
	NM_010786.4	NP_034916.1	12	1684
GenBank mRNA	AK004719.1	-	12	1643
	AK004881.1	-	10	2826
	AK088638.1	-	12	1614
	AK150530.1	-	10	1375
	AK152685.1	-	10	1375
	AK168690.1	-	12	1667
	BC050902.1	-	12	1600	6415937
	BC092270.1	-	12	1631	4018419
	DQ344919.1	-	1	25
	U47934.1	-	10	1390
	X58876.1	-	12	1591

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108099, XM_008765396, XM_008765397, XM_008765399, XM_006241382, and others.

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of gene expression
negative regulation of gene expression
negative regulation of protein processing
protein ubiquitination
peptidyl-lysine modification
protein catabolic process
protein destabilization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
positive regulation of protein export from nucleus
negative regulation of cell cycle arrest
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
scaffold protein binding