156867

• Gene Symbol: Slc11a1
• Gene Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
• Gene Aliases: Bcg, Ity, Lsh, Nramp, Nramp1, ity
• Chromosome Location: Chr.1: 74375014 - 74386057 on Build GRCm38
• UniGene ID: Mm.2913
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Slc11a1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013612.2	NP_038640.2	12	1395
GenBank mRNA	AK090303.1	-	11	1675
	AK144237.1	-	12	1380
	AK171343.1	-	9	1820
	AK171393.1	-	12	1376
	BC109137.1	-	12	1309	40039390
	BC109138.1	-	12	1309	40039397
	L13732.1	-	12	1373
	X75355.1	-	12	1354

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001031658, XM_006245220, XM_006245219, BC100653.

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
MAPK cascade
negative regulation of cytokine production
positive regulation of cytokine production
T cell proliferation involved in immune response
T cell cytokine production
positive regulation of dendritic cell antigen processing and presentation
positive regulation of T-helper 1 type immune response
transport
ion transport
iron ion transport
manganese ion transport
cellular cadmium ion homeostasis
cellular iron ion homeostasis
phagocytosis
inflammatory response
vacuolar acidification
response to bacterium
positive regulation of gene expression
nitrite transport
activation of protein kinase activity
response to lipopolysaccharide
interleukin-2 production
interleukin-3 production
positive regulation of interferon-gamma production
response to interferon-gamma
wound healing
macrophage activation
defense response to bacterium
defense response to protozoan
L-arginine import
MHC class II biosynthetic process
respiratory burst
positive regulation of transcription from RNA polymerase II promoter
antigen processing and presentation of peptide antigen
mRNA stabilization
positive regulation of phagocytosis
defense response to Gram-negative bacterium
iron ion homeostasis
multicellular organismal iron ion homeostasis
cadmium ion transmembrane transport
divalent metal ion export
manganese ion transmembrane transport
hydrogen ion transmembrane transport

Function(s)

transporter activity
manganese ion transmembrane transporter activity
protein homodimerization activity
transition metal ion transmembrane transporter activity
metal ion:proton antiporter activity