156974

• Gene Symbol: Mre11a
• Gene Name: meiotic recombination 11 homolog A (S. cerevisiae)
• Gene Aliases: Mre11, Mre11b
• Chromosome Location: Chr.9: 14784670 - 14837125 on Build GRCm38
• UniGene ID: Mm.149071
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mre11a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_018736.2	NP_061206.1	6	655
GenBank mRNA	AK041248.1	-	6	654
	AK141214.1	-	6	667
	AK146234.1	-	6	688
	AK146370.1	-	6	688
	AK168180.1	-	6	688
	AK168208.1	-	6	689
	BC065144.1	-	6	655	30627207
	U58987.1	-	6	690
	U60318.1	-	6	690

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022279, XM_006242532, XM_006242534, XM_006242533, AF218574.

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
DNA repair
base-excision repair
double-strand break repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
sister chromatid cohesion
mitotic G2 DNA damage checkpoint
synapsis
cell proliferation
intra-S DNA damage checkpoint
positive regulation of protein autophosphorylation
DNA duplex unwinding
negative regulation of DNA endoreduplication
positive regulation of kinase activity
negative regulation of viral entry into host cell
chromosome organization
meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis

Function(s)

single-stranded DNA endodeoxyribonuclease activity
DNA binding
ATP-dependent DNA helicase activity
nuclease activity
endonuclease activity
endodeoxyribonuclease activity
exonuclease activity
protein C-terminus binding
3'-5' exonuclease activity
hydrolase activity
manganese ion binding