157052

• Gene Symbol: Kit
• Gene Name: kit oncogene
• Gene Aliases: Bs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT
• Chromosome Location: Chr.5: 75574987 - 75656722 on Build GRCm38
• UniGene ID: Mm.247073
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Kit
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001122733.1	NP_001116205.1	6, 7	1188
	NM_021099.3	NP_066922.2	6, 7	1184
GenBank mRNA	AK046795.1	-	6, 7	1180
	AK047010.1	-	6, 7	1184
	AK145462.1	-	3, 4	425
	AY536430.1	-	6, 7	1147
	AY536431.1	-	6, 7	1147
	BC026713.1	-	6, 7	1167
	BC052457.1	-	6, 7	1159	6830637
	BC075716.1	-	6, 7	1173	3673641
	Y00864.1	-	6, 7	1151

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022264, XM_006250909, D12524, EU247828, EU247827.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
ovarian follicle development
myeloid progenitor cell differentiation
lymphoid progenitor cell differentiation
immature B cell differentiation
dendritic cell cytokine production
mast cell chemotaxis
myeloid leukocyte differentiation
protein phosphorylation
glycosphingolipid metabolic process
chemotaxis
inflammatory response
transmembrane receptor protein tyrosine kinase signaling pathway
germ cell development
spermatogenesis
spermatid development
positive regulation of cell proliferation
germ cell migration
regulation of cell shape
visual learning
response to radiation
positive regulation of gene expression
phosphorylation
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
lamellipodium assembly
hemopoiesis
cell differentiation
T cell differentiation
erythrocyte differentiation
melanocyte differentiation
positive regulation of cell migration
positive regulation of pseudopodium assembly
actin cytoskeleton reorganization
mast cell cytokine production
somatic stem cell population maintenance
embryonic hemopoiesis
ectopic germ cell programmed cell death
intracellular signal transduction
megakaryocyte development
Fc receptor signaling pathway
Kit signaling pathway
erythropoietin-mediated signaling pathway
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of programmed cell death
mast cell degranulation
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
pigmentation
positive regulation of Notch signaling pathway
positive regulation of JAK-STAT cascade
protein autophosphorylation
developmental pigmentation
regulation of developmental pigmentation
somatic stem cell division
positive regulation of long-term neuronal synaptic plasticity
digestive tract development
stem cell differentiation
epithelial cell proliferation
detection of mechanical stimulus involved in sensory perception of sound
positive regulation of sequence-specific DNA binding transcription factor activity
cell chemotaxis
mast cell differentiation
cellular response to thyroid hormone stimulus
melanocyte migration
melanocyte adhesion

Function(s)

nucleotide binding
protease binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
stem cell factor receptor activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
cytokine binding
protein homodimerization activity
metal ion binding