157372

• Gene Symbol: Ercc1
• Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 1
• Gene Aliases: Ercc-1
• Chromosome Location: Chr.7: 19344422 - 19356524 on Build GRCm38
• UniGene ID: Mm.280913
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ercc1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007948.2	NP_031974.2	8	860
GenBank mRNA	AK088271.1	-	8	832
	AK136733.1	-	8	820
	BC011224.1	-	8	830	4039274
	X07414.1	-	8	825

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106228, XM_006228396, XM_006228395, FQ225470.

Panther Classification:

Molecular Function -

endodeoxyribonuclease

Gene Ontology Categories:

Process(es)

pyrimidine dimer repair by nucleotide-excision repair
replicative cell aging
DNA repair
nucleotide-excision repair
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
double-strand break repair
DNA recombination
mitotic recombination
syncytium formation
cellular response to DNA damage stimulus
response to oxidative stress
germ cell development
spermatogenesis
cell proliferation
male gonad development
UV protection
response to X-ray
multicellular organism aging
negative regulation of telomere maintenance
post-embryonic hemopoiesis
multicellular organism growth
interstrand cross-link repair
isotype switching
cell development
oogenesis
chromosome organization

Function(s)

single-stranded DNA endodeoxyribonuclease activity
TFIID-class transcription factor binding
DNA binding
damaged DNA binding
single-stranded DNA binding
nuclease activity
endonuclease activity
protein binding
protein C-terminus binding
hydrolase activity
TBP-class protein binding
protein domain specific binding
structure-specific DNA binding