157447

• Gene Symbol: Ptk2
• Gene Name: PTK2 protein tyrosine kinase 2
• Gene Aliases: FAK, FRNK, Fadk, mKIAA4203, p125FAK
• Chromosome Location: Chr.15: 73205102 - 73423275 on Build GRCm38
• UniGene ID: Mm.254494
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptk2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130409.1	NP_001123881.1	18, 19	1889
	NM_007982.2	NP_032008.2	17, 18	1734
GenBank mRNA	AB011499.1	-	18, 19	1545
	AK079821.1	-	18, 19	1986
	AK220543.1	-	17, 18	1734
	BC030180.1	-	18, 19	1819
	JN971016.1	-	17, 18	1461
	M95408.1	-	16, 17	1531

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001199649, NM_005607, NM_153831, BC035404, AB209083, and others.

Gene Ontology Categories:

Process(es)

MAPK cascade
microtubule cytoskeleton organization
angiogenesis
blood vessel development
vasculogenesis
neuron migration
regulation of protein phosphorylation
positive regulation of protein phosphorylation
protein phosphorylation
movement of cell or subcellular component
cell adhesion
signal complex assembly
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
JNK cascade
multicellular organism development
positive regulation of cell proliferation
regulation of cell shape
regulation of epithelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
phosphorylation
peptidyl-tyrosine phosphorylation
central nervous system neuron axonogenesis
negative regulation of cell-cell adhesion
regulation of cell adhesion
extracellular matrix organization
positive regulation of cell growth
positive regulation of cell migration
negative regulation of cell migration
cellular chloride ion homeostasis
regulation of cell adhesion mediated by integrin
peptidyl-tyrosine autophosphorylation
establishment of nucleus localization
regulation of cell proliferation
negative regulation of apoptotic process
endothelial cell migration
innate immune response
regulation of osteoblast differentiation
positive regulation of cell adhesion
positive regulation of protein kinase activity
positive regulation of vasodilation
negative regulation of organ growth
protein autophosphorylation
ephrin receptor signaling pathway
positive regulation of smooth muscle cell proliferation
positive regulation of phagocytosis
negative regulation of axonogenesis
positive regulation of synaptic transmission
regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of synapse assembly
positive regulation of glial cell proliferation
growth hormone receptor signaling pathway
cellular response to transforming growth factor beta stimulus
regulation of substrate adhesion-dependent cell spreading
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of anoikis

Function(s)

nucleotide binding
actin binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer activity
receptor binding
integrin binding
protein binding
ATP binding
JUN kinase binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein complex binding
SH2 domain binding
identical protein binding
phosphatidylinositol 3-kinase binding