157457

• Gene Symbol: Fap
• Gene Name: fibroblast activation protein
• Gene Aliases: SIMP
• Chromosome Location: Chr.2: 62500936 - 62575508 on Build GRCm38
• UniGene ID: Mm.41816
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fap
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007986.3	NP_032012.1	4, 5	459
GenBank mRNA	AK051959.1	-	4, 5	362
	AK136578.1	-	3, 4	449
	BC019190.1	-	4, 5	363	5028579
	Y10007.1	-	4, 5	459

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_138850, BC061713, AF493782.

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

angiogenesis
proteolysis
apoptotic process
cell adhesion
regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
endothelial cell migration
proteolysis involved in cellular protein catabolic process
negative regulation of cell proliferation involved in contact inhibition
positive regulation of cell cycle arrest
mitotic cell cycle arrest
melanocyte proliferation
positive regulation of execution phase of apoptosis
melanocyte apoptotic process
negative regulation of extracellular matrix organization

Function(s)

protease binding
endopeptidase activity
serine-type endopeptidase activity
integrin binding
peptidase activity
serine-type peptidase activity
dipeptidyl-peptidase activity
hydrolase activity
protein homodimerization activity