157491

• Gene Symbol: Fen1
• Gene Name: flap structure specific endonuclease 1
• Gene Aliases: AW538437, FEN-1
• Chromosome Location: Chr.19: 10199132 - 10204187 on Build GRCm38
• UniGene ID: Mm.2952
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fen1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271614.1	NP_001258543.1	2	1627
	NM_001271615.1	NP_001258544.1	2	1522
	NM_007999.4	NP_032025.2	2	1638
GenBank mRNA	AK042942.1	-	2	1471
	AK046256.1	-	2	1634
	AK076977.1	-	2	1613
	AK078778.1	-	2	1625
	AK153889.1	-	2	1605
	AK161047.1	-	2	1618
	AK166948.1	-	2	1606
	AK168731.1	-	2	1630
	BC010203.1	-	2	1568	3158176
	BC027295.1	-	2	1502	3985840
	L26320.1	-	1	1459

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053430, XM_006231072, XM_008760246, XM_006231073, XM_006231074, and others.

Panther Classification:

Molecular Function -

exodeoxyribonuclease

Gene Ontology Categories:

Process(es)

DNA metabolic process
DNA replication
DNA repair
cellular response to DNA damage stimulus
memory
DNA replication, removal of RNA primer
nucleic acid phosphodiester bond hydrolysis
RNA phosphodiester bond hydrolysis, endonucleolytic

Function(s)

magnesium ion binding
DNA binding
catalytic activity
nuclease activity
endonuclease activity
RNA-DNA hybrid ribonuclease activity
exonuclease activity
5'-3' exonuclease activity
hydrolase activity
hydrolase activity, acting on ester bonds
5'-flap endonuclease activity
manganese ion binding
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
metal ion binding
flap endonuclease activity