158294

• Gene Symbol: Il2
• Gene Name: interleukin 2
• Gene Aliases: Il-2
• Chromosome Location: Chr.3: 37120713 - 37125954 on Build GRCm38
• UniGene ID: Mm.14190
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Il2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008366.3	NP_032392.1	2	280
GenBank mRNA	AF065914.1	-	2	278
	AF065915.1	-	2	278
	AF065916.1	-	2	278
	AY147902.1	-	2	232
	BC116845.1	-	2	278	40126164
	BC116873.1	-	2	278	40126192
	DQ836354.1	-	2	172
	K02292.1	-	2	280
	U41494.1	-	2	175
	U41504.1	-	2	190
	U41505.1	-	2	202
	U41506.1	-	2	175
	X01772.1	-	2	279
	X73040.1	-	2	279

More Information

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
immune system process
negative regulation of B cell apoptotic process
immune response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
positive regulation of B cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of T cell differentiation
positive regulation of regulatory T cell differentiation
negative regulation of heart contraction
positive regulation of transcription from RNA polymerase II promoter
regulation of T cell homeostatic proliferation
positive regulation of isotype switching to IgG isotypes
negative regulation of lymphocyte proliferation
negative regulation of inflammatory response
positive regulation of immunoglobulin secretion
positive regulation of dendritic spine development
extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

cytokine activity
interleukin-2 receptor binding
growth factor activity
carbohydrate binding
kappa-type opioid receptor binding
glycosphingolipid binding