158473

• Gene Symbol: Fadd
• Gene Name: Fas (TNFRSF6)-associated via death domain
• Gene Aliases: Mort1/FADD
• Chromosome Location: Chr.7: 144578323 - 144582436 on Build GRCm38
• UniGene ID: Mm.5126
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fadd
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010175.5	NP_034305.1	2	609
GenBank mRNA	AK007648.1	-	2	636
	AK031396.1	-	2	610
	AK084808.1	-	2	610
	AK169798.1	-	2	637
	AK170927.1	-	2	636
	BC004584.1	-	2	599	3587331
	BC021400.1	-	2	606	4190229
	U43184.1	-	2	562
	U50406.1	-	2	574

More Information

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
immune system process
positive regulation of adaptive immune response
apoptotic process
signal transduction
T cell differentiation
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
T cell differentiation in thymus
TRAIL-activated apoptotic signaling pathway
positive regulation of activated T cell proliferation
regulation of apoptotic process
T cell homeostasis
positive regulation of apoptotic process
innate immune response
positive regulation of macrophage differentiation
positive regulation of proteolysis
positive regulation of transcription from RNA polymerase II promoter
lymph node development
spleen development
thymus development
cardiac muscle tissue development
protein heterooligomerization
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
negative regulation of necroptotic process
negative regulation of activation-induced cell death of T cells
motor neuron apoptotic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
necroptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
tumor necrosis factor receptor binding
protein binding
protein complex binding
tumor necrosis factor receptor superfamily binding
death effector domain binding
identical protein binding