158688

• Gene Symbol: Gdnf
• Gene Name: glial cell line derived neurotrophic factor
• Gene Aliases: AI385739
• Chromosome Location: Chr.15: 7810048 - 7837580 on Build GRCm38
• UniGene ID: Mm.4679
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gdnf
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001301332.1	NP_001288261.1	3	1231
	NM_001301333.1	NP_001288262.1	3	593
	NM_001301357.1	NP_001288286.1	2	281
	NM_010275.3	NP_034405.1	3	1309
GenBank mRNA	BC119031.1	-	3	325	8733780
	D49921.1	-	2	216
	D88264.1	-	3	511
	U37459.1	-	3	346
	U75532.1	-	3	348

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001278098, NM_001190468, NM_000514, NM_199231, NM_001190469, and others.

Panther Classification:

Molecular Function -

neurotrophic factor

Gene Ontology Categories:

Process(es)

metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
neural crest cell migration
organ induction
postsynaptic membrane organization
mesenchymal to epithelial transition involved in metanephros morphogenesis
transmembrane receptor protein tyrosine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
nervous system development
peripheral nervous system development
cell proliferation
positive regulation of cell proliferation
response to wounding
regulation of gene expression
postganglionic parasympathetic fiber development
neuron differentiation
peristalsis
neuron projection development
positive regulation of monooxygenase activity
negative regulation of neuron apoptotic process
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mRNA stabilization
enteric nervous system development
sympathetic nervous system development
regulation of dopamine uptake involved in synaptic transmission
ureteric bud formation
regulation of morphogenesis of a branching structure
cellular response to dexamethasone stimulus
regulation of ureteric bud formation
positive regulation of ureteric bud formation
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

transforming growth factor beta receptor binding
growth factor activity
glial cell-derived neurotrophic factor receptor binding
protein homodimerization activity