158941

• Gene Symbol: Hey1
• Gene Name: hairy/enhancer-of-split related with YRPW motif 1
• Gene Aliases: AI316788, AI414254, CHF2, HRT1, Herp2, Hesr1, bHLHb31, hesr-1
• Chromosome Location: Chr.3: 8663359 - 8667038 on Build GRCm38
• UniGene ID: Mm.29581
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hey1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010423.2	NP_034553.2	3, 4	422
GenBank mRNA	AB041590.1	-	3, 4	315
	AF151521.1	-	3, 4	370
	AF172286.1	-	3, 4	403
	AF176423.1	-	3, 4	384
	AF232241.1	-	3, 4	402
	AJ243895.1	-	3, 4	370
	AK011149.1	-	3, 4	424
	AK140212.1	-	3, 4	423
	BC086635.1	-	3, 4	408	6809680

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_012258, AJ272214, AK313271, AF232239, AK074641, and others.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
vasculogenesis
osteoblast development
outflow tract morphogenesis
atrioventricular valve morphogenesis
pulmonary valve morphogenesis
atrioventricular valve formation
epithelial to mesenchymal transition involved in endocardial cushion formation
endocardial cushion to mesenchymal transition involved in heart valve formation
endocardial cushion morphogenesis
cardiac ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
Notch signaling pathway
multicellular organism development
anterior/posterior axis specification
negative regulation of gene expression
mesenchymal cell development
dorsal aorta morphogenesis
umbilical cord morphogenesis
negative regulation of neuron differentiation
positive regulation of osteoblast differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cardiac epithelial to mesenchymal transition
cardiac septum morphogenesis
ventricular septum morphogenesis
labyrinthine layer blood vessel development
artery development
arterial endothelial cell differentiation
Notch signaling involved in heart development
negative regulation of transcription regulatory region DNA binding
negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
regulation of vasculogenesis

Function(s)

transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, protein binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
microsatellite binding
sequence-specific DNA binding
protein dimerization activity