159114

• Gene Symbol: Igf1r
• Gene Name: insulin-like growth factor I receptor
• Gene Aliases: A330103N21Rik, CD221, D930020L01, IGF-1R, hyft
• Chromosome Location: Chr.7: 67952257 - 68233668 on Build GRCm38
• UniGene ID: Mm.275742
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Igf1r
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010513.2	NP_034643.2	2	733
GenBank mRNA	AF056187.1	-	2	131
	BC138868.1	-	2	163	8861890
	BC138869.1	-	2	163	8861891
	U00182.1	-	2	133

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000875, BC113610, BC113612, EU826611, AB425196, and others.
This siRNA also targets the following transcripts in Rat: NM_052807, XM_008759500, XM_006229324, M27293, L29232.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

protein phosphorylation
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
axonogenesis
brain development
epidermis development
organ morphogenesis
negative regulation of muscle cell apoptotic process
phosphorylation
establishment of cell polarity
male sex determination
positive regulation of cell migration
mammary gland development
exocrine pancreas development
neuron projection development
positive regulation of cytokinesis
peptidyl-tyrosine autophosphorylation
negative regulation of apoptotic process
negative regulation of MAPK cascade
positive regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of DNA replication
positive regulation of mitotic nuclear division
regulation of JNK cascade
protein autophosphorylation
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of DNA metabolic process
protein tetramerization
protein heterooligomerization
inactivation of MAPKK activity
positive regulation of protein kinase B signaling
negative regulation of protein kinase B signaling
prostate gland epithelium morphogenesis
positive regulation of steroid hormone biosynthetic process

Function(s)

nucleotide binding
G-protein alpha-subunit binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
insulin-like growth factor-activated receptor activity
insulin receptor binding
protein binding
insulin-like growth factor binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
insulin-like growth factor I binding
identical protein binding
phosphatidylinositol 3-kinase binding
insulin binding
insulin receptor substrate binding