159138

• Gene Symbol: Ikbkb
• Gene Name: inhibitor of kappaB kinase beta
• Gene Aliases: AI132552, IKK-2, IKK-beta, IKK2, IKK[b], IKKbeta
• Chromosome Location: Chr.8: 22659205 - 22706585 on Build GRCm38
• UniGene ID: Mm.277886
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ikbkb
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001159774.1	NP_001153246.1	3	252
	NM_010546.2	NP_034676.1	3	252
GenBank mRNA	AF026524.1	-	2	120
	AF088910.1	-	3	312
	AK011359.1	-	3	219
	AK053346.1	-	3	246
	AK086442.1	-	3	248
	AK139972.1	-	3	210
	AK144048.1	-	3	229
	AK144603.1	-	3	245
	AK150884.1	-	3	204
	AK151888.1	-	3	204
	AK151955.1	-	3	204
	AK153151.1	-	3	204
	AK155587.1	-	3	204
	AK156294.1	-	3	210
	AK201390.1	-	1	30
	BC004772.1	-	3	190
	BC037723.1	-	3	224	4482634
	BY015258.1	-	3	254

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

B cell homeostasis
protein phosphorylation
I-kappaB phosphorylation
positive regulation of cell proliferation
positive regulation of sodium ion transport
phosphorylation
signal transduction by protein phosphorylation
neuron projection development
serine phosphorylation of STAT protein
positive regulation of transcription from RNA polymerase II promoter
positive regulation of NF-kappaB transcription factor activity
cellular response to tumor necrosis factor
positive regulation of neuron death
positive regulation of cation channel activity

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding