159277

• Gene Symbol: Ptpn6
• Gene Name: protein tyrosine phosphatase, non-receptor type 6
• Gene Aliases: 70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
• Chromosome Location: Chr.6: 124720707 - 124738709 on Build GRCm38
• UniGene ID: Mm.271799
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptpn6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001077705.2	NP_001071173.1	7	976
	NM_013545.3	NP_038573.2	7	974
GenBank mRNA	AK132509.1	-	7	893
	AK150509.1	-	7	881
	AK151077.1	-	7	895
	AK151623.1	-	7	898
	AK159686.1	-	7	933
	AK159833.1	-	7	926
	AK167923.1	-	7	928
	AK169804.1	-	7	976
	BC012660.1	-	7	919	4010462
	M68902.1	-	7	926
	M90389.1	-	7	876

More Information

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

hematopoietic progenitor cell differentiation
negative regulation of humoral immune response mediated by circulating immunoglobulin
protein dephosphorylation
signal transduction
cell proliferation
positive regulation of cell proliferation
positive regulation of phosphatidylinositol 3-kinase signaling
dephosphorylation
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
cell differentiation
platelet formation
abortive mitotic cell cycle
positive regulation of cell adhesion mediated by integrin
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
megakaryocyte development
negative regulation of T cell proliferation
natural killer cell mediated cytotoxicity
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
regulation of B cell differentiation
negative regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
regulation of release of sequestered calcium ion into cytosol
regulation of ERK1 and ERK2 cascade
platelet aggregation
regulation of G1/S transition of mitotic cell cycle

Function(s)

phosphotyrosine binding
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
hydrolase activity
phosphatase activity
SH3 domain binding
protein kinase binding
SH2 domain binding
natural killer cell lectin-like receptor binding