159626

• Gene Symbol: Alox12
• Gene Name: arachidonate 12-lipoxygenase
• Gene Aliases: 9930022G08Rik, Alox12p, P-12LO
• Chromosome Location: Chr.11: 70241455 - 70255386 on Build GRCm38
• UniGene ID: Mm.12286
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Alox12
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007440.4	NP_031466.2	5	642
GenBank mRNA	AK036898.1	-	5	640
	AK036960.1	-	5	598
	AK079232.1	-	5	643
	AK087724.1	-	5	643
	AK172216.1	-	5	640
	AK172488.1	-	5	643
	BC152329.1	-	5	647	40141477
	BC152403.1	-	5	647	40141482
	S77511.1	-	3	199
	S80446.1	-	5	654
	U04334.1	-	5	573

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105798, XM_006246659, BC168184.

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

lipid metabolic process
fatty acid metabolic process
movement of cell or subcellular component
positive regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
positive regulation of cell death
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
hepoxilin biosynthetic process
positive regulation of mitochondrial depolarization
oxidation-reduction process
establishment of skin barrier
negative regulation of platelet aggregation
lipoxin A4 biosynthetic process
lipoxin B4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
juvenile hormone epoxide hydrolase activity
linoleate 13S-lipoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
hydrolase activity
epoxide hydrolase B activity
phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity
epoxide hydrolase A activity
phenanthrene-3,4-epoxide hydrolase activity
phenanthrene-1,2-epoxide hydrolase activity
phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity
phenanthrene-epoxide hydrolase activity
phenanthrene-9,10-epoxide hydrolase activity
pyrene-4,5-epoxide hydrolase activity
metal ion binding
dioxygenase activity