159807

• Gene Symbol: Bak1
• Gene Name: BCL2-antagonist/killer 1
• Gene Aliases: Bak, N-BAK1, N-Bak
• Chromosome Location: Chr.17: 27019812 - 27028839 on Build GRCm38
• UniGene ID: Mm.2443
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bak1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007523.2	NP_031549.2	3	365
GenBank mRNA	AF402617.1	-	2	112
	AK089220.1	-	3	303
	BC057589.1	-	3	317	6411580
	CX564692.1	-	3	298
	Y13231.1	-	3	366

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053812, XM_006256101, AF259504, BC089784.

Gene Ontology Categories:

Process(es)

leukocyte homeostasis
B cell homeostasis
B cell apoptotic process
release of cytochrome c from mitochondria
blood vessel remodeling
myeloid cell homeostasis
B cell negative selection
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
mitochondrial fusion
cell proliferation
negative regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
response to fungus
response to mycotoxin
establishment or maintenance of transmembrane electrochemical gradient
response to gamma radiation
positive regulation of calcium ion transport into cytosol
negative regulation of gene expression
cytolysis
negative regulation of endoplasmic reticulum calcium ion concentration
negative regulation of peptidyl-serine phosphorylation
cellular response to UV
limb morphogenesis
regulation of apoptotic process
positive regulation of apoptotic process
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
fibroblast apoptotic process
positive regulation of proteolysis
regulation of mitochondrial membrane permeability
post-embryonic camera-type eye morphogenesis
homeostasis of number of cells
regulation of cell cycle
regulation of mitochondrial membrane potential
vagina development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
thymocyte apoptotic process
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
positive regulation of endoplasmic reticulum unfolded protein response
apoptotic process involved in patterning of blood vessels

Function(s)

protein binding
heat shock protein binding
identical protein binding
protein homodimerization activity
metal ion binding
protein heterodimerization activity
chaperone binding
BH domain binding