160234

• Gene Symbol: Clock
• Gene Name: circadian locomotor output cycles kaput
• Gene Aliases: 5330400M04Rik, KAT13D
• Chromosome Location: Chr.5: 76209868 - 76305007 on Build GRCm38
• UniGene ID: Mm.3552
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Clock
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001289826.1	NP_001276755.1	6	489
	NM_007715.6	NP_031741.1	6	532
GenBank mRNA	AB221635.1	-	3	144
	AF000998.1	-	6	532
	AK030352.1	-	6	454
	AK040337.1	-	6	470
	AK041303.1	-	6	470
	AK129118.1	-	6	489
	AK158765.1	-	6	470
	BC129886.1	-	4	241

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_021856, NM_001289832, XM_006250870, XM_006250869, AB019259, and others.

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
signal transduction
spermatogenesis
circadian rhythm
histone acetylation
circadian regulation of gene expression
regulation of hair cycle
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of inflammatory response
regulation of insulin secretion
positive regulation of NF-kappaB transcription factor activity
response to redox state
cellular response to ionizing radiation
regulation of type B pancreatic cell development
negative regulation of glucocorticoid receptor signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
histone acetyltransferase activity
signal transducer activity
protein binding
transcription factor binding
transferase activity
transferase activity, transferring acyl groups
chromatin DNA binding
sequence-specific DNA binding
protein dimerization activity
E-box binding