1603

• Gene Symbol: MYLK
• Gene Name: myosin light chain kinase
• Gene Aliases: AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
• Chromosome Location: Chr.3: 123612296 - 123884302 on Build GRCh38
• UniGene ID: Hs.477375
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MYLK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001321309.1	NP_001308238.1	32	5476
	NM_053025.3	NP_444253.3	33	5684
	NM_053026.3	NP_444254.3	32	5477
	NM_053027.3	NP_444255.3	32	5531
	NM_053028.3	NP_444256.3	31	5324
	XM_011512860.2	XP_011511162.1	30	5402
	XM_011512861.2	XP_011511163.1	29	5201
	XM_017006469.1	XP_016861958.1	16	2960
	XM_017006470.1	XP_016861959.1	15	1948
	XM_017006471.1	XP_016861960.1	15	2001
	XM_017006472.1	XP_016861961.1	3	294
	XM_017006473.1	XP_016861962.1	3	243
GenBank mRNA	AB037663.1	-	16	2760
	AF069601.2	-	30	5314
	AF069602.1	-	30	5365
	AF069603.1	-	29	5158
	AF069604.1	-	10	1340
	AF096773.1	-	2	318
	AF096774.1	-	2	315
	AF096775.1	-	2	318
	AK300610.1	-	15	1934
	AK314412.1	-	2	329
	AK314443.1	-	2	372
	AL832211.1	-	2	3906
	AY339601.1	-	30	5402
	AY424269.1	-	29	5197
	AY424270.1	-	30	5404
	BC017811.1	-	2	339
	BC064420.1	-	2	358
	BC100761.2	-	2	200
	BC100762.1	-	2	200
	BC100763.1	-	2	197
	BC107783.1	-	2	342
	BC113456.1	-	2	163
	BC113458.1	-	2	160
	CR749364.1	-	2	5144
	DB016380.1	-	2	437
	U48959.2	-	31	5521
	X85337.1	-	17	3014
	X90870.1	-	8	1034

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105874, XM_006248433, XM_008768712, XM_008768711, XM_006248434.
This siRNA also targets the following transcripts in Mouse: NM_139300, AK162008, BC058610, AK078556, BC037721, and others.

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
protein phosphorylation
muscle contraction
smooth muscle contraction
tonic smooth muscle contraction
positive regulation of cell migration
bleb assembly
positive regulation of calcium ion transport
aorta smooth muscle tissue morphogenesis
cellular hypotonic response
positive regulation of wound healing
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

actin binding
myosin light chain kinase activity
protein binding
calmodulin binding
ATP binding
metal ion binding