160566

• Gene Symbol: Dnm2
• Gene Name: dynamin 2
• Gene Aliases: Dyn2, Udnm, b2b2159Clo
• Chromosome Location: Chr.9: 21424908 - 21507759 on Build GRCm38
• UniGene ID: Mm.433257
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dnm2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039520.2	NP_001034609.1	3, 4	575
	NM_001253893.1	NP_001240822.1	3, 4	575
	NM_001253894.1	NP_001240823.1	3, 4	575
	NM_007871.2	NP_031897.2	3, 4	575
GenBank mRNA	AK005012.2	-	3, 4	551
	AK015410.1	-	2, 3	240
	AK150046.1	-	3, 4	538
	AK154375.1	-	2, 3	239
	AK157844.1	-	3, 4	545
	AK170574.1	-	3, 4	551
	AK171049.1	-	3, 4	529
	AK171566.1	-	3, 4	539
	AK172231.1	-	3, 4	556
	L31398.1	-	3, 4	515

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013199, XM_006242614, XM_006242611, XM_006242613, XM_008765917, and others.

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

G-protein coupled receptor internalization
Golgi to plasma membrane transport
endocytosis
receptor-mediated endocytosis
positive regulation of lamellipodium assembly
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of axon extension
receptor internalization
transferrin transport
regulation of Rac protein signal transduction
macropinocytosis
positive regulation of nitric oxide biosynthetic process
positive regulation of endocytosis
neuron projection morphogenesis
positive regulation of phagocytosis
cilium morphogenesis
positive regulation of substrate adhesion-dependent cell spreading
cellular response to dopamine
regulation of Golgi organization
positive regulation of sodium:potassium-exchanging ATPase activity
negative regulation of membrane tubulation

Function(s)

nucleotide binding
GTPase activity
protein binding
GTP binding
hydrolase activity
SH3 domain binding
protein kinase binding
D2 dopamine receptor binding
protein complex binding
phosphatidylinositol 3-kinase regulatory subunit binding
WW domain binding
nitric-oxide synthase binding