160618

• Gene Symbol: E2f1
• Gene Name: E2F transcription factor 1
• Gene Aliases: E2F-1, mKIAA4009
• Chromosome Location: Chr.2: 154559400 - 154569892 on Build GRCm38
• UniGene ID: Mm.18036
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: E2f1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291105.1	NP_001278034.1	7	1352
	NM_007891.5	NP_031917.1	7	1396
GenBank mRNA	AF483514.1	-	7	1238
	AF483515.1	-	7	1238
	AK017841.1	-	7	1344
	AK153968.1	-	7	1361
	AK220226.1	-	7	1093
	BC052160.1	-	7	1338	6330425
	L21973.1	-	7	1356

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001100778, XM_008762363.

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
cell cycle
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of gene expression
forebrain development
anoikis
negative regulation of DNA binding
negative regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
mRNA stabilization
regulation of cell cycle
negative regulation of fat cell proliferation
cellular response to xenobiotic stimulus
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
intrinsic apoptotic signaling pathway by p53 class mediator
lens fiber cell apoptotic process
cellular response to nerve growth factor stimulus
regulation of G1/S transition of mitotic cell cycle

Function(s)

core promoter binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein kinase binding
sequence-specific DNA binding
transcription regulatory region DNA binding