160640

• Gene Symbol: Alox12b
• Gene Name: arachidonate 12-lipoxygenase, 12R type
• Gene Aliases: Aloxe2, e-LOX2
• Chromosome Location: Chr.11: 69157072 - 69169791 on Build GRCm38
• UniGene ID: Mm.340329
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Alox12b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009659.2	NP_033789.1	1	281
GenBank mRNA	AF059251.1	-	1	159
	BC113149.1	-	1	245	40054352
	Y14334.1	-	1	281

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001039377, AY903232, AY903233, AY903231.

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

protein lipidation
lipid metabolic process
fatty acid metabolic process
sphingolipid metabolic process
positive regulation of gene expression
arachidonic acid metabolic process
lipoxygenase pathway
positive regulation of MAPK cascade
linoleic acid metabolic process
ceramide biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
establishment of skin barrier
positive regulation of mucus secretion
bicellular tight junction assembly

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
2,3-dihydroxy DDT 1,2-dioxygenase activity
phenanthrene dioxygenase activity
2,2',3-trihydroxybiphenyl dioxygenase activity
1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity
1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity
protocatechuate 3,4-dioxygenase type II activity
2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity
3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity
2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity
carbazole 1,9a-dioxygenase activity
dihydroxydibenzothiophene dioxygenase activity
1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity
styrene dioxygenase activity
3,4-dihydroxyphenanthrene dioxygenase activity
hydroquinone 1,2-dioxygenase activity
p-cumate 2,3-dioxygenase activity
2,3-dihydroxy-p-cumate dioxygenase activity
3,5-dichlorocatechol 1,2-dioxygenase activity
2-aminophenol 1,6-dioxygenase activity
2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity
chlorocatechol 1,2-dioxygenase activity
catechol dioxygenase activity
dihydroxyfluorene dioxygenase activity
5-aminosalicylate dioxygenase activity
3-hydroxy-2-naphthoate 2,3-dioxygenase activity
benzo(a)pyrene 11,12-dioxygenase activity
benzo(a)pyrene 4,5-dioxygenase activity
4,5-dihydroxybenzo(a)pyrene dioxygenase activity
benzo(a)pyrene 9,10-dioxygenase activity
9,10-dihydroxybenzo(a)pyrene dioxygenase activity
benzo(a)pyrene 7,8-dioxygenase activity
7,8-dihydroxy benzo(a)pyrene dioxygenase activity
1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity
2-mercaptobenzothiazole dioxygenase activity
pyridine-3,4-diol dioxygenase activity
pyrene dioxygenase activity
4,5-dihydroxypyrene dioxygenase activity
phenanthrene-4-carboxylate dioxygenase activity
tetrachlorobenzene dioxygenase activity
4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity
2,3-dihydroxydiphenyl ether dioxygenase activity
diphenyl ether 1,2-dioxygenase activity
arachidonate 8(S)-lipoxygenase activity
metal ion binding
4-hydroxycatechol 1,2-dioxygenase activity
dioxygenase activity
linoleate 9S-lipoxygenase activity