160700

• Gene Symbol: Apaf1
• Gene Name: apoptotic peptidase activating factor 1
• Gene Aliases: 6230400I06Rik, Apaf-1, Apaf1l, fog, mKIAA0413
• Chromosome Location: Chr.10: 90989311 - 91082743 on Build GRCm38
• UniGene ID: Mm.220289
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Apaf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042558.1	NP_001036023.1	8	1720
	NM_001282947.1	NP_001269876.1	8	1644
	NM_009684.2	NP_033814.2	8	1677
GenBank mRNA	AF064071.1	-	8	1604
	AK220340.1	-	8	1716
	BC083191.1	-	8	1596
	BC131683.1	-	8	1236	40111198
	BC131684.1	-	8	1236	40111199

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001160, NM_013229, NM_181868, NM_181861, AJ243008, and others.
This siRNA also targets the following transcripts in Rat: NM_023979, XM_008765263, AF218388, AF320222.

Gene Ontology Categories:

Process(es)

neural tube closure
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
multicellular organism development
brain development
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
cardiac muscle cell apoptotic process
forebrain development
regulation of apoptotic process
protein homooligomerization
neuron apoptotic process
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to transforming growth factor beta stimulus
apoptotic signaling pathway
regulation of apoptotic DNA fragmentation
positive regulation of apoptotic signaling pathway

Function(s)

nucleotide binding
ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
heat shock protein binding
identical protein binding
ADP binding