160776

• Gene Symbol: Atf4
• Gene Name: activating transcription factor 4
• Gene Aliases: Atf-4, C/ATF, CREB2, TAXREB67
• Chromosome Location: Chr.15: 80255184 - 80257545 on Build GRCm38
• UniGene ID: Mm.641
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Atf4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001287180.1	NP_001274109.1	4	943
	NM_009716.3	NP_033846.2	3	1226
GenBank mRNA	AB012277.1	-	1	374
	AK003001.1	-	3	1230
	AK138657.1	-	3	911
	AK144777.1	-	3	912
	AK146193.1	-	3	914
	AK150231.1	-	3	914
	AK155254.1	-	3	912
	AK156298.1	-	3	906
	AK177669.1	-	1	178
	AK192031.1	-	1	157
	AK204555.1	-	1	125
	BC031542.1	-	1	1520
	BC085169.1	-	3	1117	30551592
	L13791.1	-	2	731
	M94087.1	-	3	893
	X61507.1	-	3	903

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_024403, FQ210065, FQ214151, FQ221881, FQ215912, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

gluconeogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
gamma-aminobutyric acid signaling pathway
positive regulation of vascular endothelial growth factor production
positive regulation of gene expression
circadian regulation of gene expression
cellular response to amino acid starvation
response to endoplasmic reticulum stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
PERK-mediated unfolded protein response
cellular response to glucose starvation
negative regulation of potassium ion transport
positive regulation of neuron apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase I promoter
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
negative regulation of oxidative stress-induced neuron death
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
transcription factor binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity