161026

• Gene Symbol: Runx1
• Gene Name: runt related transcription factor 1
• Gene Aliases: AML1, CBF-alpha-2, Cbfa2, Pebp2a2, Pebpa2b
• Chromosome Location: Chr.16: 92601466 - 92826074 on Build GRCm38
• UniGene ID: Mm.4081
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Runx1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001111021.2	NP_001104491.1	8	1779
	NM_001111022.2	NP_001104492.1	7	1587
	NM_001111023.2	NP_001104493.1	6	3114
	NM_009821.3	NP_033951.2	5	2922
GenBank mRNA	AK051758.1	-	5	2460
	AK137493.1	-	8	1749
	AK153274.1	-	1	165
	AK165307.1	-	8	1774
	BC069929.1	-	7	1523	4008335
	D26532.1	-	5	2919

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017325, XM_008768598, XM_008768599, L35271.

Panther Classification:

Molecular Function -

Runt transcription factor

Gene Ontology Categories:

Process(es)

skeletal system development
in utero embryonic development
liver development
myeloid progenitor cell differentiation
regulation of T cell anergy
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
central nervous system development
negative regulation of cell proliferation
regulation of signal transduction
hemopoiesis
myeloid cell differentiation
neuron differentiation
negative regulation of granulocyte differentiation
positive regulation of granulocyte differentiation
hair follicle morphogenesis
response to retinoic acid
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
embryonic hemopoiesis
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
behavioral response to pain
neuron development
definitive hemopoiesis
regulation of hair follicle cell proliferation
cellular response to transforming growth factor beta stimulus
positive regulation of cell maturation
positive regulation of progesterone secretion

Function(s)

regulatory region DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
calcium ion binding
protein binding
ATP binding
transcription factor binding
protein homodimerization activity
protein heterodimerization activity
repressing transcription factor binding