161495

• Gene Symbol: Dkk1
• Gene Name: dickkopf homolog 1 (Xenopus laevis)
• Gene Aliases: mdkk-1
• Chromosome Location: Chr.19: 30545876 - 30549496 on Build GRCm38
• UniGene ID: Mm.214717
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dkk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010051.3	NP_034181.2	4	1026
GenBank mRNA	AF030433.1	-	4	945
	AK141693.1	-	4	1050
	AK144119.1	-	4	1052
	BC050189.1	-	4	1026	30022799
	JN966751.1	-	4	1079

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106350, XM_003749089, JN966752.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis involved in differentiation
endoderm formation
mesoderm formation
hair follicle development
regulation of receptor internalization
multicellular organism development
endoderm development
Wnt signaling pathway
regulation of Wnt signaling pathway
negative regulation of Wnt signaling pathway
embryonic limb morphogenesis
negative regulation of BMP signaling pathway
forebrain development
negative regulation of protein complex assembly
response to retinoic acid
negative regulation of peptidyl-serine phosphorylation
negative regulation of mesodermal cell fate specification
regulation of endodermal cell fate specification
negative regulation of skeletal muscle tissue development
head morphogenesis
face morphogenesis
negative regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
extracellular negative regulation of signal transduction
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
negative regulation of receptor activity
negative regulation of cardiac muscle cell differentiation

Function(s)

protein binding
receptor antagonist activity
low-density lipoprotein particle receptor binding