162169

• Gene Symbol: Adra2a
• Gene Name: adrenergic receptor, alpha 2a
• Gene Aliases: AW122659, Adra-2, Adra-2a, alpha(2A)AR, alpha2-C10, alpha2A, alpha2A-AR
• Chromosome Location: Chr.19: 54045182 - 54048982 on Build GRCm38
• UniGene ID: Mm.235195
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Adra2a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007417.4	NP_031443.4	1	1659
GenBank mRNA	AK046802.1	-	2	1453
	AK140461.1	-	2	1453
	AK141573.1	-	1	1612
	BC138531.1	-	1	1275	8861551

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012739, U79031.

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

positive regulation of cytokine production
acute inflammatory response
DNA replication
G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
cell-cell signaling
female pregnancy
negative regulation of norepinephrine secretion
positive regulation of cell migration
negative regulation of cAMP biosynthetic process
activation of protein kinase activity
activation of protein kinase B activity
cellular response to hormone stimulus
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
glucose homeostasis
fear response
positive regulation of MAP kinase activity
positive regulation of epidermal growth factor-activated receptor activity
positive regulation of vasodilation
negative regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
thermoception
negative regulation of lipid catabolic process
positive regulation of membrane protein ectodomain proteolysis
negative regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of uterine smooth muscle contraction
adrenergic receptor signaling pathway
adenylate cyclase-inhibiting adrenergic receptor signaling pathway
phospholipase C-activating adrenergic receptor signaling pathway
activation of MAPK activity by adrenergic receptor signaling pathway
positive regulation of wound healing

Function(s)

adrenergic receptor activity
alpha2-adrenergic receptor activity
protein kinase binding
alpha-2C adrenergic receptor binding
thioesterase binding
heterotrimeric G-protein binding
protein homodimerization activity
protein heterodimerization activity
epinephrine binding
norepinephrine binding