1622 Validated

• Gene Symbol: NPR1
• Gene Name: natriuretic peptide receptor 1
• Gene Aliases: ANPRA, ANPa, GUC2A, GUCY2A, NPRA
• Chromosome Location: Chr.1: 153678617 - 153693992 on Build GRCh38
• UniGene ID: Hs.490330
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NPR1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000906.3	NP_000897.3	5	1609
	XM_005245218.1	XP_005245275.1	5	1680
	XM_017001374.1	XP_016856863.1	5	1680
GenBank mRNA	AK025024.1	-	5	1609
	AK300446.1	-	4	815
	BC063304.1	-	5	1658	30331757
	X15357.1	-	5	1231

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012613, XM_006232591, BC128742, X14773.
This siRNA also targets the following transcripts in Mouse: NM_008727, BC110659, J05504, BC139767, L31932.

Matching Taqman Gene Expression Assay:

Hs00418568_m1

Panther Classification:

Molecular Function -

guanylate cyclase

Gene Ontology Categories:

Process(es)

cGMP biosynthetic process
protein phosphorylation
cell surface receptor signaling pathway
receptor guanylyl cyclase signaling pathway
G-protein coupled receptor signaling pathway
body fluid secretion
regulation of blood pressure
negative regulation of angiogenesis
negative regulation of cell growth
positive regulation of cGMP biosynthetic process
intracellular signal transduction
positive regulation of urine volume
positive regulation of renal sodium excretion
regulation of vasodilation
dopamine metabolic process
regulation of vascular permeability
negative regulation of smooth muscle cell proliferation
regulation of cardiac conduction

Function(s)

adenylate cyclase activity
guanylate cyclase activity
protein kinase activity
ATP binding
GTP binding
G-protein coupled peptide receptor activity
natriuretic peptide receptor activity
peptide hormone binding
protein kinase binding
hormone binding