162263

Gene Symbol:

Ppargc1a Asic2

Gene Name:

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

acid-sensing (proton-gated) ion channel 2

Gene Aliases:

A830037N07Rik, ENSMUSG00000079510, Gm11133, PGC-1, PGC-1v, Pgc-1alpha, Pgc1, Pgco1, Ppargc1

ACIC2, Accn1, BNC1, BNaC1, BNaC1a, Mdeg

Chromosome Location:

Chr.5: 51454249 - 52115958 on Build GRCm38

Chromosome Location:

Chr.11: 80880163 - 81968396 on Build GRCm38

UniGene ID:

Mm.259072

Mm.234998

Species:

Mouse

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Ppargc1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008904.2	NP_032930.1	3	453
GenBank mRNA	AB061324.1	-	3	376
	AF049330.1	-	3	405
	AK138668.1	-	3	454
	AK143753.1	-	3	405
	BC066868.1	-	3	348	30094033
	JX866948.1	-	3	341

Gene Symbol: Asic2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	EF410098.1	-		520

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_013261, AF159714, JQ772117, AF186379, AK296591, and others.
This siRNA also targets the following transcripts in Rat: NM_031347, XM_008770220, XM_008770219, AB025784, AY237127.

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to dietary excess
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
mitochondrion organization
positive regulation of mitochondrion organization
response to muscle activity
negative regulation of smooth muscle cell migration
respiratory electron transport chain
positive regulation of cellular metabolic process
circadian regulation of gene expression
cellular response to oxidative stress
regulation of circadian rhythm
negative regulation of neuron apoptotic process
cellular respiration
negative regulation of glycolytic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fatty acid oxidation
rhythmic process
positive regulation of smooth muscle cell proliferation
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of neuron death
positive regulation of cellular respiration
positive regulation of mitochondrial DNA metabolic process
positive regulation of muscle tissue development
negative regulation of receptor activity
regulation of N-methyl-D-aspartate selective glutamate receptor activity
positive regulation of energy homeostasis
positive regulation of ATP biosynthetic process

Function(s)

nucleotide binding
RNA polymerase II transcription cofactor activity
nucleic acid binding
DNA binding
chromatin binding
transcription coactivator activity
RNA binding
protein binding
transcription factor binding
ligand-dependent nuclear receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
chromatin DNA binding
ubiquitin protein ligase binding
sequence-specific DNA binding