164725

• Gene Symbol: Rac1
• Gene Name: RAS-related C3 botulinum substrate 1
• Gene Aliases: AL023026, D5Ertd559e
• Chromosome Location: Chr.5: 143505481 - 143528116 on Build GRCm38
• UniGene ID: Mm.292510
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rac1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009007.2	NP_033033.1	3, 4	432
GenBank mRNA	AK008435.1	-	3, 4	433
	AK009017.1	-	3, 4	433
	AK011072.2	-	3, 4	433
	AK034601.1	-	3, 4	433
	AK047969.1	-	3, 4	435
	AK076023.1	-	3, 4	474
	AK088825.1	-	3, 4	444
	AK166383.1	-	4, 5	496
	BC003828.1	-	3, 4	433	3593957
	BC051053.1	-	3, 4	432	5038182
	CX242948.1	-	3, 4	469
	JN971018.1	-	3, 4	236
	X57277.1	-	3, 4	376

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_134366, XM_008768986, AY491395, AF385833.

Panther Classification:

Molecular Function -

small GTPase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
auditory receptor cell morphogenesis
mast cell chemotaxis
epithelial cell morphogenesis
endocytosis
phagocytosis, engulfment
chemotaxis
hyperosmotic response
cytoskeleton organization
actin filament organization
cell adhesion
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
axon guidance
metabolic process
cell proliferation
positive regulation of lamellipodium assembly
regulation of fibroblast migration
positive regulation of cell-substrate adhesion
regulation of neuron maturation
dendrite development
cell migration
cerebral cortex radially oriented cell migration
embryonic olfactory bulb interneuron precursor migration
cerebral cortex GABAergic interneuron development
regulation of cell morphogenesis
lamellipodium assembly
actin cytoskeleton organization
actin filament polymerization
regulation of cell migration
positive regulation of actin filament polymerization
ruffle organization
negative regulation of interleukin-23 production
substrate adhesion-dependent cell spreading
positive regulation of phosphatidylinositol 3-kinase activity
engulfment of apoptotic cell
cell-cell junction organization
bone resorption
positive regulation of DNA replication
anatomical structure arrangement
dendrite morphogenesis
cell motility
homeostasis of number of cells within a tissue
positive regulation of stress fiber assembly
localization within membrane
positive regulation of focal adhesion assembly
synaptic transmission, GABAergic
Wnt signaling pathway, planar cell polarity pathway
regulation of respiratory burst
cellular response to mechanical stimulus
semaphorin-plexin signaling pathway
dopaminergic neuron differentiation
protein localization to plasma membrane
positive regulation of neutrophil chemotaxis
cochlea morphogenesis
ruffle assembly
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

nucleotide binding
GTPase activity
protein binding
GTP binding
Rab GTPase binding
enzyme binding
protein kinase binding
GTP-dependent protein binding
thioesterase binding
histone deacetylase binding
Rho GDP-dissociation inhibitor binding