166168

• Gene Symbol: Trem2
• Gene Name: triggering receptor expressed on myeloid cells 2
• Gene Aliases: TREM-2, Trem2a, Trem2b, Trem2c
• Chromosome Location: Chr.17: 48346401 - 48352276 on Build GRCm38
• UniGene ID: Mm.261623
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Trem2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001272078.1	NP_001259007.1	2, 3	553
	NM_031254.3	NP_112544.1	2, 3	553
GenBank mRNA	AF213458.1	-	2, 3	464
	AK039477.1	-	2, 3	458
	AK155163.1	-	2, 3	467
	AK171358.1	-		2376
	AY024348.1	-	2, 3	473
	AY024349.1	-	2, 3	398
	AY187009.1	-	2, 3	420
	BC032959.1	-	2, 3	442	1348066
	BC033485.1	-	2, 3	464	4953284
	BC052784.1	-	2, 3	562	5057491

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106884, XM_006244425, XM_006244424, FQ229837.

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

positive regulation of antigen processing and presentation of peptide antigen via MHC class II
signal transduction
lipopolysaccharide-mediated signaling pathway
detection of lipopolysaccharide
detection of peptidoglycan
innate immune response
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of calcium-mediated signaling
positive regulation of ERK1 and ERK2 cascade
detection of lipoteichoic acid
cellular response to lipoteichoic acid
cellular response to peptidoglycan
dendritic cell differentiation
positive regulation of protein localization to plasma membrane
positive regulation of C-C chemokine receptor CCR7 signaling pathway
positive regulation of CD40 signaling pathway

Function(s)

lipopolysaccharide binding
transmembrane signaling receptor activity
protein binding
peptidoglycan binding
lipoteichoic acid binding
scaffold protein binding