166365

• Gene Symbol: Pkn1
• Gene Name: protein kinase N1
• Gene Aliases: DBK, F730027O18Rik, PAK1, PRK1, Pkn, Prkcl1, Stk3
• Chromosome Location: Chr.8: 83669762 - 83699179 on Build GRCm38
• UniGene ID: Mm.213000
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pkn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199593.1	NP_001186522.1	4	613
	NM_177262.4	NP_796236.2	4	724
GenBank mRNA	AK089431.1	-	4	588
	AK134792.1	-	5	708
	AK149649.1	-	4	587
	AK150062.1	-	4	550
	AK170556.1	-	4	681
	AK171297.1	-	4	596
	BC052923.1	-	4	671	6312892

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_213560, NM_002741, BC040061, BC094766, S75546, and others.
This siRNA also targets the following transcripts in Rat: NM_017175, XM_006255245, D26180, BC061836, L35634, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

B cell homeostasis
B cell apoptotic process
negative regulation of protein phosphorylation
regulation of germinal center formation
regulation of immunoglobulin production
renal system process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epithelial cell migration
phosphorylation
chromatin modification
negative regulation of B cell proliferation
histone H3-T11 phosphorylation
spleen development
regulation of cell motility

Function(s)

nucleotide binding
chromatin binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein kinase C binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
GTP-Rho binding
ligand-dependent nuclear receptor transcription coactivator activity
histone kinase activity (H3-T11 specific)
histone binding
histone deacetylase binding
Rac GTPase binding
androgen receptor binding