16641

• Gene Symbol: REST
• Gene Name: RE1 silencing transcription factor
• Gene Aliases: NRSF, WT6, XBR
• Chromosome Location: Chr.4: 56907876 - 56935847 on Build GRCh38
• UniGene ID: Hs.307836
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: REST
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001193508.1	NP_001180437.1	2	445
	NM_005612.4	NP_005603.3	2	656
	XM_011534401.2	XP_011532703.1	2	763
	XM_017008527.1	XP_016864016.1	2	617
GenBank mRNA	AB209750.1	-	2	396
	BC017822.1	-	2	347
	BC038985.1	-	2	585
	BC132859.1	-	2	332	40146881
	BC136491.1	-	2	332	9020480
	JX896957.1	-	2	438
	JX896958.1	-	2	438
	JX896959.1	-	2	438
	JX896966.1	-	2	342
	JX896967.1	-	3	98
	JX896970.1	-	2	345
	JX896971.1	-	2	438
	JX896981.1	-	2	342
	JX896983.1	-	2	438
	JX896984.1	-	2	438
	JX896989.1	-	2	342
	JX896990.1	-	2	345
	JX896991.1	-	2	438
	JX896992.1	-	2	342
	JX896993.1	-	2	345
	U13877.1	-	1	319
	U13879.1	-	2	556
	U22314.1	-	1	358

More Information

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
hematopoietic progenitor cell differentiation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of cell proliferation
negative regulation of gene expression
negative regulation of aldosterone biosynthetic process
cellular response to drug
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation by host of viral transcription
negative regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
negative regulation of neurogenesis
cardiac muscle cell myoblast differentiation
histone H4 deacetylation
cellular response to electrical stimulus
cellular response to glucocorticoid stimulus
potassium ion transmembrane transport
negative regulation of cortisol biosynthetic process
negative regulation of dense core granule biogenesis
negative regulation of mesenchymal stem cell differentiation
negative regulation of amniotic stem cell differentiation

Function(s)

core promoter sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
transcription factor binding
outward rectifier potassium channel activity
protein complex binding
transcription regulatory region DNA binding
metal ion binding