16709

• Gene Symbol: RAD50
• Gene Name: RAD50 double strand break repair protein
• Gene Aliases: NBSLD, RAD502, hRad50
• Chromosome Location: Chr.5: 132556924 - 132644621 on Build GRCh38
• UniGene ID: Hs.633509
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RAD50
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005732.3	NP_005723.2	2, 3	622
GenBank mRNA	AF057299.1	-	2, 3	542
	AF057300.1	-	2, 3	542
	AK290597.1	-	2, 3	564
	AK307439.1	-	2, 3	297
	BC062603.1	-	2, 3	539
	BC073850.1	-	2, 3	539
	BC108282.1	-	2, 3	559
	BC136436.1	-	2, 3	514	9020425
	BC140005.1	-	2, 3	616
	DQ655928.2	-	2, 3	225
	U63139.1	-	2, 3	609

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022246, FQ232550, AF218576.

Gene Ontology Categories:

Process(es)

regulation of mitotic recombination
telomere maintenance via recombination
telomere maintenance
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
DNA recombination
cellular response to DNA damage stimulus
telomere maintenance via telomerase
reciprocal meiotic recombination
viral process
telomeric 3' overhang formation
positive regulation of protein autophosphorylation
positive regulation of telomere maintenance
DNA duplex unwinding
positive regulation of kinase activity
nucleotide phosphorylation
chromosome organization involved in meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
negative regulation of telomere capping

Function(s)

single-stranded DNA endodeoxyribonuclease activity
DNA binding
double-stranded telomeric DNA binding
ATP-dependent DNA helicase activity
adenylate kinase activity
protein binding
ATP binding
3'-5' exonuclease activity
protein binding, bridging
single-stranded telomeric DNA binding
metal ion binding
G-quadruplex DNA binding