16747

• Gene Symbol: SOS1
• Gene Name: SOS Ras/Rac guanine nucleotide exchange factor 1
• Gene Aliases: GF1, GGF1, GINGF, HGF, NS4
• Chromosome Location: Chr.2: 38981549 - 39124959 on Build GRCh38
• UniGene ID: Hs.709893
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005633.3	NP_005624.2	4	424
	XM_005264515.4	XP_005264572.1	4	653
	XM_011533062.2	XP_011531364.1	4	592
	XM_011533064.2	XP_011531366.1	4	332
GenBank mRNA	AK290228.1	-	5	470
	AK301960.1	-	4	483
	L13857.1	-	4	383

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001100716.
This siRNA also targets the following transcripts in Mouse: NM_009231, AK140310.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

MAPK cascade
B cell homeostasis
hair follicle development
cardiac atrium morphogenesis
pericardium morphogenesis
signal transduction
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
vitellogenesis
axon guidance
insulin receptor signaling pathway
regulation of T cell differentiation in thymus
regulation of Rho protein signal transduction
multicellular organism growth
Fc-epsilon receptor signaling pathway
ERBB2 signaling pathway
regulation of T cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
positive regulation of epidermal growth factor receptor signaling pathway
neurotrophin TRK receptor signaling pathway
blood vessel morphogenesis
leukocyte migration
regulation of small GTPase mediated signal transduction
positive regulation of small GTPase mediated signal transduction
palate development
eyelid development in camera-type eye
heart trabecula morphogenesis
midbrain morphogenesis
regulation of pro-B cell differentiation

Function(s)

DNA binding
guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
SH3 domain binding
protein heterodimerization activity