172146

• Gene Symbol: Raf1
• Gene Name: v-raf-leukemia viral oncogene 1
• Gene Aliases: 6430402F14Rik, AA990557, BB129353, Craf1, D830050J10Rik, Raf-1, c-Raf, v-Raf
• Chromosome Location: Chr.6: 115618573 - 115677129 on Build GRCm38
• UniGene ID: Mm.184163
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Raf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_029780.3	NP_084056.1	2	580
GenBank mRNA	AB057655.1	-	1	125
	AB057663.2	-	2	350
	AB077145.1	-	2	350
	AK036317.1	-	2	467
	AK141745.1	-	2	581
	BC015273.1	-	2	459	4222659
	BC056439.1	-	2	499
	BC092040.1	-	2	445	2645313

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012639, XM_008763217, XM_008763218, M15427, BC062071.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
response to hypoxia
cellular glucose homeostasis
positive regulation of protein phosphorylation
protein phosphorylation
signal transduction
negative regulation of cell proliferation
phosphorylation
cell differentiation
negative regulation of protein complex assembly
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
intracellular signal transduction
insulin secretion involved in cellular response to glucose stimulus
response to muscle stretch
negative regulation of apoptotic process
intermediate filament cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
neurotrophin TRK receptor signaling pathway
death-inducing signaling complex assembly
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
receptor signaling protein activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Ras GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
metal ion binding
protein heterodimerization activity