172245

• Gene Symbol: Egln2
• Gene Name: egl-9 family hypoxia-inducible factor 2
• Gene Aliases: 0610011A13Rik, C85656, Hif-p4h-1, Ier4, Phd1, SM-20
• Chromosome Location: Chr.7: 27158658 - 27166802 on Build GRCm38
• UniGene ID: Mm.29978
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Egln2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053208.4	NP_444438.2	5	1540
GenBank mRNA	AF340231.1	-	4	1282
	AF453879.1	-	5	1462
	AJ310547.1	-	5	1511
	AK075582.1	-	5	1492
	AK152056.1	-	5	1501
	AK152223.1	-	5	1498
	AK159206.1	-	5	1493
	AK166661.1	-	6	1406
	AK167477.1	-	5	1493
	BC023299.1	-	5	1474	5135579
	BC051436.1	-	4	1258	6312638
	BC086764.1	-	5	1479	5685311

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001004083, XM_006228575, XM_006228574, BC081858, AY952204, and others.

Gene Ontology Categories:

Process(es)

response to hypoxia
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
regulation of neuron apoptotic process
cell redox homeostasis
positive regulation of protein catabolic process
oxidation-reduction process

Function(s)

iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxygen sensor activity
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 4-dioxygenase activity
metal ion binding
dioxygenase activity