173111

• Gene Symbol: Mthfd1
• Gene Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
• Gene Aliases: Dcs, E430024A07Rik, Mthfd
• Chromosome Location: Chr.12: 76255232 - 76319820 on Build GRCm38
• UniGene ID: Mm.29584
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mthfd1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_138745.2	NP_620084.2	4	479
GenBank mRNA	AF364579.1	-	4	260
	AK042019.1	-	4	359
	AK042958.1	-	4	315
	AK088700.1	-	4	276
	AK129012.1	-	4	413
	AK133848.1	-	3	214
	AK159812.1	-	4	291
	AK165951.1	-	4	311
	AK180541.1	-	4	197
	BC008523.1	-	4	303	3590449
	CD545120.1	-	4	479

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022508, XM_008762232, XM_006240249, BC089800, J05519.

Gene Ontology Categories:

Process(es)

histidine biosynthetic process
neutrophil homeostasis
neural tube closure
purine nucleotide biosynthetic process
methionine metabolic process
one-carbon metabolic process
heart development
metabolic process
cellular amino acid biosynthetic process
serine family amino acid metabolic process
serine family amino acid biosynthetic process
methionine biosynthetic process
10-formyltetrahydrofolate biosynthetic process
folic acid-containing compound biosynthetic process
transsulfuration
tetrahydrofolate interconversion
oxidation-reduction process
somite development

Function(s)

nucleotide binding
catalytic activity
formate-tetrahydrofolate ligase activity
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase (NAD+) activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
ATP binding
oxidoreductase activity
hydrolase activity
ligase activity