17581

• Gene Symbol: CD28
• Gene Name: CD28 molecule
• Gene Aliases: Tp44
• Chromosome Location: Chr.2: 203706475 - 203739756 on Build GRCh38
• UniGene ID: Hs.443123
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CD28
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243077.1	NP_001230006.1	4	1918
	NM_001243078.1	NP_001230007.1	3	1852
	NM_006139.3	NP_006130.1	4	2209
	XM_011512194.2	XP_011510496.1	4	2044
	XM_011512195.2	XP_011510497.1	5	1786
	XM_011512197.2	XP_011510499.1	5	1808

More Information

Panther Classification:

Molecular Function -

immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

positive regulation of inflammatory response to antigenic stimulus
humoral immune response
cell surface receptor signaling pathway
positive regulation of gene expression
negative regulation of gene expression
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
T cell costimulation
positive regulation of interleukin-10 production
positive regulation of interleukin-4 production
cytokine biosynthetic process
positive regulation of T cell proliferation
negative thymic T cell selection
regulatory T cell differentiation
positive regulation of viral genome replication
positive regulation of interleukin-2 biosynthetic process
regulation of regulatory T cell differentiation
positive regulation of translation
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
positive regulation of alpha-beta T cell proliferation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of isotype switching to IgG isotypes
regulation of defense response to virus by virus
T cell receptor signaling pathway
positive regulation of protein kinase B signaling
apoptotic signaling pathway

Function(s)

protease binding
SH3/SH2 adaptor activity
protein binding
coreceptor activity
protein kinase binding
identical protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity