179088

• Gene Symbol: Optn
• Gene Name: optineurin
• Gene Aliases: 4930441O07Rik, FIP2, HYPL, NRP
• Chromosome Location: Chr.2: 5020520 - 5064112 on Build GRCm38
• UniGene ID: Mm.116942
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Optn
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_181848.4	NP_862896.1	2, 3	220
GenBank mRNA	AY071834.1	-	2, 3	327
	BC061185.1	-	2, 3	220	30314331

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_021980, NM_001008211, NM_001008212, NM_001008213, AF061034, and others.
This siRNA also targets the following transcripts in Rat: NM_145081, XM_006254263, XM_006254262, XM_006254264, XM_008771853, and others.

Gene Ontology Categories:

Process(es)

protein targeting to Golgi
negative regulation of receptor recycling
autophagy
Golgi organization
positive regulation of cell proliferation
macroautophagy
cellular protein localization
Golgi to plasma membrane protein transport
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of neuron apoptotic process
cytokine secretion
defense response to Gram-negative bacterium
protein homooligomerization
Golgi ribbon formation

Function(s)

TFIIIA-class transcription factor binding
protein binding
protein C-terminus binding
Rab GTPase binding
polyubiquitin binding
identical protein binding
ubiquitin binding
K63-linked polyubiquitin binding